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Intelligent Cell Processing

Advancing Cell Therapy Through Intelligent Automation

Cell therapies present a unique manufacturing challenge: processes must be controlled and reproducible while accommodating the inherent variability of living cells.

Celligent was built for that challenge.

Our BioAdaptive Automation™ combines robotics, image processing algorithms, precision cell manipulation, and intelligent workflow management to execute complex processes around the biology of the cells.

Already deployed in manufacturing workflows, Celligent provides a GMP-compatible foundation that can extend across process development, characterization, scale-up, and manufacturing.

One technology foundation from process development to GMP manufacturing.

— Applications

Supporting the Next Generation of Cell-Based Products

  • Autologous Cell Therapies

    Support individualized iPSC manufacturing workflows where reproducibility, traceability, process control, and efficient execution are critical.

  • Allogeneic Cell Therapies

    Support multivariate process development with structured longitudinal data to accelerate process development, characterization and optimization, and enable reliable scale-up.

  • Tissue Engineering & Regenerative Medicine

    Automate complex cell-processing workflows supporting tissues engineering and regenerative therapeutic products.

  • Organoids & Advanced Cell Models

    Enable reproducible, longitudinally monitored workflows for complex biological models and extended culture.

  • Emerging Cell-Based Therapeutics

    A flexible automation architecture designed to support evolving cell-based products and manufacturing strategies.

Celligent™ Cell Processing Platform

Automation Built Around the Biology

Celligent is designed to automate cell culture much as an experienced operator performs it today—without requiring developers to reinvent established biological workflows around fundamentally different processing technologies.

The platform translates familiar cell-culture operations into controlled automated execution, including feeding, media exchange, passaging, imaging, sampling, colony selection, precision cell removal, and other workflow-specific operations.

Combined with the Workflow Manager, this enables complex processes to be automated around their biological requirements while preserving the principles of established manual workflows.

A risk-based approach to automation can reduce operator-dependent variability and human error while improving consistency, traceability, and utilization of skilled personnel.

Less variability • Fewer manual interventions • Greater consistency • Reduced time and cost

— Celligent Advantages

Consistency Through Intelligent Execution

Automation

The foundation of success lies in the critical beginning stages. We strongly emphasize ensuring your starting materials are optimized for success, safety, and efficacy by integrating automated controls to sharply reduce human error and contamination events. Our cutting-edge Celligent platform employs ‘BioAdaptive Automation™’, which means that weeding, picking, biopsying, media changing, and passaging are automated in response to biological cues such as confluency or colony size, thus adjusting to account for cells’ inherent variability.

With Celligent, you gain access to a comprehensive suite of features – from sample preparation to cell culturing and beyond – that ensure precise and reproducible results every time.

— Atraumatic picking & biopsying
— Imaging
— Positive & negative cell selection

Process Intelligence

Turn Process Data Into Process Understanding

Every automated run generates structured, longitudinal evidence about both the process and the biology.

Celligent connects process parameters, workflow history, imaging, culture behavior, sampling, and analytical results to create a reliable foundation for process development and characterization, supporting:

Process Development • Characterization • Optimization • Scale-Up • Manufacturability

Better data enables better process decisions.

Digital Process Record

Capture the Process as It Happens

Celligent automatically captures the history of the process as it is executed.

Automated batch records connect workflow actions, timestamps, imaging, culture and sample lineage, operator interactions, and process information within a traceable digital record.

Longitudinal imaging • Process actions • Timing • Cell lineage • Selection events • Sampling • Process parameters • Analytical results

21 CFR Part 11-compliant software provides the data integrity and traceability required for regulated GMP workflows.

Don't reconstruct the process after the fact. Capture it as it happens.

Intelligent Cell Processing

From Complex Biology to Controlled Manufacturing

Celligent™ is a GMP-compatible automation platform built for complex cell therapy processes – with manufacturing workflows already deployed today.

Celligent combines intelligent automation, imaging, workflow management, single-use consumables, automated batch records, and 21 CFR Part 11-compliant software to deliver greater consistency, traceability, and process control.

Execute the process. Capture the evidence. Understand the biology. Manufacture with confidence.

Advancing Cell Therapy Through Intelligent Automation

Cell therapies present a unique manufacturing challenge: processes must be controlled and reproducible while accommodating the inherent variability of living cells.

Celligent was built for that challenge.

Our BioAdaptive Automation™ combines robotics, image processing algorithms, precision cell manipulation, and intelligent workflow management to execute complex processes around the biology of the cells.

Already deployed in manufacturing workflows, Celligent provides a GMP-compatible foundation that can extend across process development, characterization, scale-up, and manufacturing.

One technology foundation from process development to GMP manufacturing.

Applications

Supporting the Next Generation of Cell-Based Products
  • Autologous Cell Therapies

    Support individualized iPSC manufacturing workflows where reproducibility, traceability, process control, and efficient execution are critical.

  • Allogeneic Cell Therapies

    Support multivariate process development with structured longitudinal data to accelerate process development, characterization and optimization, and enable reliable scale-up.

  • Tissue Engineering & Regenerative Medicine

    Automate complex cell-processing workflows supporting tissues engineering and regenerative therapeutic products.

  • Organoids & Advanced Cell Models

    Enable reproducible, longitudinally monitored workflows for complex biological models and extended culture.

  • Emerging Cell-Based Therapeutics

    A flexible automation architecture designed to support evolving cell-based products and manufacturing strategies.

Celligent™ Cell Processing Platform

Automation Built Around the Biology

Celligent is designed to automate cell culture much as an experienced operator performs it today—without requiring developers to reinvent established biological workflows around fundamentally different processing technologies.

The platform translates familiar cell-culture operations into controlled automated execution, including feeding, media exchange, passaging, imaging, sampling, colony selection, precision cell removal, and other workflow-specific operations.

Combined with the Workflow Manager, this enables complex processes to be automated around their biological requirements while preserving the principles of established manual workflows.

A risk-based approach to automation can reduce operator-dependent variability and human error while improving consistency, traceability, and utilization of skilled personnel.

Less variability • Fewer manual interventions • Greater consistency • Reduced time and cost

— Celligent Advantages

Consistency Through Intelligent Execution

Automation

The foundation of success lies in the critical beginning stages. We strongly emphasize ensuring your starting materials are optimized for success, safety, and efficacy by integrating automated controls to sharply reduce human error and contamination events. Our cutting-edge Celligent platform employs ‘BioAdaptive Automation™’, which means that weeding, picking, biopsying, media changing, and passaging are automated in response to biological cues such as confluency or colony size, thus adjusting to account for cells’ inherent variability.

With Celligent, you gain access to a comprehensive suite of features – from sample preparation to cell culturing and beyond – that ensure precise and reproducible results every time.

— Atraumatic picking & biopsying
— Imaging
— Positive & negative cell selection

Process Intelligence

Turn Process Data Into Process Understanding

Every automated run generates structured, longitudinal evidence about both the process and the biology.

Celligent connects process parameters, workflow history, imaging, culture behavior, sampling, and analytical results to create a reliable foundation for process development and characterization, supporting:

Process Development • Characterization • Optimization • Scale-Up • Manufacturability

Better data enables better process decisions.

Digital Process Record

Capture the Process as It Happens

Celligent automatically captures the history of the process as it is executed.

Automated batch records connect workflow actions, timestamps, imaging, culture and sample lineage, operator interactions, and process information within a traceable digital record.

Longitudinal imaging • Process actions • Timing • Cell lineage • Selection events • Sampling • Process parameters • Analytical results

21 CFR Part 11-compliant software provides the data integrity and traceability required for regulated GMP workflows.

Don't reconstruct the process after the fact. Capture it as it happens.

What Can You Do With Celligent?

iPSC Reprogramming, Clone Selection & Cell-Line Generation

Automate reprogramming, identify and select individual colonies, and track and expand selected clones while maintaining lineage and process history—enabling greater control over cell-line generation and selection.

Differentiation

Automate extended, multistep adherent differentiation processes with longitudinal monitoring throughout the workflow.

Process Development & Optimization

Execute controlled multivariate experiments while generating structured longitudinal data to support process development, characterization, and optimization.

Cell Therapy Manufacturing

Execute controlled, automated manufacturing processes with integrated workflow management, imaging, traceability, and electronic batch records.

Develop With Manufacturing in Mind

Why develop a process on one technology and then transfer it to another for manufacturing?

Celligent can support a process across its development lifecycle using the same core automation technology:

01 Process Development
→
02 Characterization
→
03 Scale-Up
→
04 GMP Manufacturing

This continuity reduces unnecessary technology transitions while maintaining consistency in process execution, data capture, and process history.

Develop on the technology designed to manufacture.

Cell X Team

The Cell X team comprises industry veterans with diverse backgrounds in advanced therapies and industrial automation Our wealth of experience in cutting-edge technologies and groundbreaking research methodologies underscores our unwavering commitment to revolutionizing the life sciences industry. With a passion for pushing the boundaries, our team has been purpose-built to foster an environment of innovation.